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BMCBI
2007
131views more  BMCBI 2007»
13 years 9 months ago
On the detection of functionally coherent groups of protein domains with an extension to protein annotation
Background: Protein domains coordinate to perform multifaceted cellular functions, and domain combinations serve as the functional building blocks of the cell. The available metho...
William A. McLaughlin, Ken Chen, Tingjun Hou, Wei ...
BMCBI
2007
156views more  BMCBI 2007»
13 years 9 months ago
Bio: : NEXUS: a Perl API for the NEXUS format for comparative biological data
Background: Evolutionary analysis provides a formal framework for comparative analysis of genomic and other data. In evolutionary analysis, observed data are treated as the termin...
Thomas Hladish, Vivek Gopalan, Chengzhi Liang, Wei...
BMCBI
2007
219views more  BMCBI 2007»
13 years 9 months ago
MetaQTL: a package of new computational methods for the meta-analysis of QTL mapping experiments
Background: Integration of multiple results from Quantitative Trait Loci (QTL) studies is a key point to understand the genetic determinism of complex traits. Up to now many effor...
Jean-Baptiste Veyrieras, Bruno Goffinet, Alain Cha...
BMCBI
2007
143views more  BMCBI 2007»
13 years 9 months ago
Gene selection for classification of microarray data based on the Bayes error
Background: With DNA microarray data, selecting a compact subset of discriminative genes from thousands of genes is a critical step for accurate classification of phenotypes for, ...
Ji-Gang Zhang, Hong-Wen Deng
BMCBI
2007
134views more  BMCBI 2007»
13 years 9 months ago
Nearest Neighbor Networks: clustering expression data based on gene neighborhoods
Background: The availability of microarrays measuring thousands of genes simultaneously across hundreds of biological conditions represents an opportunity to understand both indiv...
Curtis Huttenhower, Avi I. Flamholz, Jessica N. La...