Background: Normalization of gene expression microarrays carrying thousands of genes is based on assumptions that do not hold for diagnostic microarrays carrying only few genes. T...
Background: Missing value estimation is an important preprocessing step in microarray analysis. Although several methods have been developed to solve this problem, their performan...
Jianjun Hu, Haifeng Li, Michael S. Waterman, Xiang...
Background: Proteomic data obtained from mass spectrometry have attracted great interest for the detection of early-stage cancer. However, as mass spectrometry data are high-dimen...
Background: The exploration of the structural topology and the organizing principles of genomebased large-scale metabolic networks is essential for studying possible relations bet...
Jing Zhao, Hong Yu, Jianhua Luo, Zhi-Wei Cao, Yi-X...
Background: Regulatory modules are segments of the DNA that control particular aspects of gene expression. Their identification is therefore of great importance to the field of mo...