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RECOMB
2009
Springer
14 years 2 months ago
Inferring the Recent Duplication History of a Gene Cluster
Abstract. Much important evolutionary activity occurs in gene clusters, where a copy of a gene may be free to evolve new functions. Computational methods to extract evolutionary in...
Giltae Song, Louxin Zhang, Tomás Vinar, Web...
RECOMB
2009
Springer
14 years 8 months ago
Evaluating Between-Pathway Models with Expression Data
Abstract. Between-Pathway Models (BPMs) are network motifs consisting of pairs of putative redundant pathways. In this paper, we show how adding another source of high-throughput d...
Benjamin J. Hescott, Mark D. M. Leiserson, Lenore ...
RECOMB
2009
Springer
14 years 2 months ago
Reconstructing Histories of Complex Gene Clusters on a Phylogeny
Abstract. Clusters of genes that have evolved by repeated segmental duplication present difficult challenges throughout genomic analysis, from sequence assembly to functional analy...
Tomás Vinar, Brona Brejová, Giltae S...
RECOMB
2009
Springer
14 years 2 months ago
Yeast Ancestral Genome Reconstructions: The Possibilities of Computational Methods
In 2006, a debate has risen on the question of the efficiency of bioinformatics methods to reconstruct mammalian ancestral genomes. Three years later, Gordon et al. (PLoS Genetics,...
Eric Tannier
RECOMB
2009
Springer
14 years 8 months ago
New Perspectives on Gene Family Evolution: Losses in Reconciliation and a Link with Supertrees
Reconciliation between a set of gene trees and a species tree is the most commonly used approach to infer the duplication and loss events in the evolution of gene families, given a...
Cedric Chauve, Nadia El-Mabrouk