In silico bioinformatics experiments involve integration of and access to computational tools and biological databases. The emerging grid computing technologies enable bioinformat...
Abstract. Despite the recent advances in Molecular Biology, the function of a large amount of proteins is still unknown. An approach that can be used in the prediction of a protein...
Eduardo P. Costa, Ana Carolina Lorena, André...
Abstract. We study a parametrized definition of gene clusters that permits control over the trade-off between increasing gene content versus conserving gene order within a cluster....
We introduce a novel parameter called container flux, which is used to measure the information sharing capacity between two distinct nodes in a graph. Other useful information, bot...
In this paper we introduce a novel approach for the analysis of microarray titration experiments. The test introduced here can be used more generally for drug-dosage effect or time...
Computational analyses of protein structure-function relationships have traditionally been based on sequence homology, fold family analysis and 3D motifs/templates. Previous struct...
Reetal Pai, James C. Sacchettini, Thomas R. Ioerge...
-- To successfully apply RNAi, the very first step is to design functional siRNA or shRNA sequences targeting specific genes. Many characteristics of functional synthetic siRNAs ha...
Background: Inferring a gene regulatory network (GRN) from high throughput biological data is often an under-determined problem and is a challenging task due to the following reas...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...