Sciweavers

BIOCOMP
2008
14 years 1 months ago
Combinations of Context-Free Shifts and Shifts of Finite Type
A Dyck shift and a Motzkin shift are mathematical models for constraints on genetic sequences. In terms of the theory of symbolic dynamics, neither of the Dyck shift nor the Motzki...
Hiroshi Kamabe
BIOCOMP
2008
14 years 1 months ago
Identifying Protein Flexibility by NMA
- Here proposed apriori method for identification of protein flexibility relies on one end-state conformation of the protein. This method has comparative advantage over many others...
Kresimir Sikic, Branko Jeren, Sanja Tomic
BIOCOMP
2008
14 years 1 months ago
Specificity Normalization for Identifying Selective Inhibitors in Virtual Screening
ct The enrichment and recall of known inhibitors in a virtual screen are correlated with the probability of finding effective inhibitors through this process. In practice, a large ...
Reetal Pai, James C. Sacchettini, Thomas R. Ioerge...
BIOCOMP
2007
14 years 1 months ago
Biomarker Discovery Across Annotated and Unannotated Microarray Datasets Using Semi-Supervised Learning
The growing body of DNA microarray data has the potential to advance our understanding of the molecular basis of disease. However annotating microarray datasets with clinically us...
Cole Harris, Noushin Ghaffari
BIOCOMP
2008
14 years 1 months ago
GIPSCo: A Method for Comparison of Protein Structures Based on Geometric Invariants
Protein structure comparison is important for elucidation of evolutionary relationships, function and functionally important amino acid residues. We propose Geometric Invariant bas...
Sandeep Deshmukh, Aniket Dalal, Pramod Wangikar
BIOCOMP
2007
14 years 1 months ago
Prediction of trans-antisense Transcripts in Arabidopsis thaliana
Background: Natural antisense transcripts (NATs) are coding or non-coding RNAs with sequence complementarity to other transcripts (sense transcripts). These RNAs could potentially...
Huan Wang, Nam-Hai Chua, Xiu-Jie Wang
BIOCOMP
2007
14 years 1 months ago
Towards Phylogenomic Reconstruction
Reconstructing phylogenies is one of the primary objectives in evolution studies. Efficient software to reconstruct phylogenies based on isolated genes has existed for decades, ye...
Le Vinh, Andres Varon, Daniel Janies, Ward Wheeler
BIOCOMP
2007
14 years 1 months ago
Learning Node Replacement Graph Grammars in Metabolic Pathways
— This paper describes graph-based relational, unsupervised learning algorithm to infer node replacement graph grammar and its application to metabolic pathways. We search for fr...
Jacek P. Kukluk, Chang Hun You, Lawrence B. Holder...
BIOCOMP
2008
14 years 1 months ago
On the Role of a Nonlinear Stress-Strain Relation in Brain Trauma
We investigate how a nonlinear stress-strain relation (that leads to a stiffening of the brain matter under strain) influences the brain dynamics in traumatic situations. We numeri...
Igor Szczyrba, Martin Burtscher, Rafal Szczyrba