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BIBM
2008
IEEE
172views Bioinformatics» more  BIBM 2008»
14 years 6 months ago
Boosting Methods for Protein Fold Recognition: An Empirical Comparison
Protein fold recognition is the prediction of protein’s tertiary structure (Fold) given the protein’s sequence without relying on sequence similarity. Using machine learning t...
Yazhene Krishnaraj, Chandan K. Reddy
BIBM
2008
IEEE
141views Bioinformatics» more  BIBM 2008»
14 years 6 months ago
Protein-Protein Interaction Network Alignment by Quantitative Simulation
We adapt a network simulation algorithm called quantitative simulation (QSim) for use in the alignment of biological networks. Unlike most network alignment methods, QSim finds l...
Perry Evans, Ted Sandler, Lyle H. Ungar
BIBM
2008
IEEE
142views Bioinformatics» more  BIBM 2008»
14 years 6 months ago
Using Global Sequence Similarity to Enhance Biological Sequence Labeling
Identifying functionally important sites from biological sequences, formulated as a biological sequence labeling problem, has broad applications ranging from rational drug design ...
Cornelia Caragea, Jivko Sinapov, Drena Dobbs, Vasa...
BIBM
2008
IEEE
217views Bioinformatics» more  BIBM 2008»
14 years 6 months ago
Combining Hierarchical Inference in Ontologies with Heterogeneous Data Sources Improves Gene Function Prediction
The study of gene function is critical in various genomic and proteomic fields. Due to the availability of tremendous amounts of different types of protein data, integrating thes...
Xiaoyu Jiang, Naoki Nariai, Martin Steffen, Simon ...
BIBM
2008
IEEE
111views Bioinformatics» more  BIBM 2008»
14 years 6 months ago
Estimating Regulatory Associations of Genomic Loci and Biological Pathways in Lymphoblastoid Cells
Genetical genomics has been established to study genetic variation of gene expression. It treats transcript expression as a quantitative trait and identifies putative regulatory l...
Jung Hoon Woo, Eunjee Lee, Sung-Bum Cho, Ju Han Ki...
BIBM
2008
IEEE
134views Bioinformatics» more  BIBM 2008»
14 years 6 months ago
New Approaches to Compare Phylogenetic Search Heuristics
We present new and novel insights into the behavior of two maximum parsimony heuristics for building evolutionary trees of different sizes. First, our results show that the heuris...
Seung-Jin Sul, Suzanne Matthews, Tiffani L. Willia...
BIBM
2008
IEEE
145views Bioinformatics» more  BIBM 2008»
14 years 6 months ago
Identifying Interface Elements Implied in Protein-Protein Interactions Using Statistical Tests and Frequent Item Sets
Understanding what are the characteristics of proteinprotein interfaces is at the core of numerous applications. This paper introduces a method in which the proteins are described...
Christine Martin, Antoine Cornuéjols
BIBM
2008
IEEE
159views Bioinformatics» more  BIBM 2008»
14 years 6 months ago
Probe Design for Compressive Sensing DNA Microarrays
Abstract—Compressive Sensing Microarrays (CSM) are DNAbased sensors that operate using group testing and compressive sensing (CS) principles. In contrast to conventional DNA micr...
Wei Dai, Olgica Milenkovic, Mona A. Sheikh, Richar...
BIBM
2008
IEEE
112views Bioinformatics» more  BIBM 2008»
14 years 6 months ago
Fast Alignments of Metabolic Networks
Network alignments are extensively used for comparing, exploring, and predicting biological networks. Existing alignment tools are mostly based on isomorphic and homeomorphic embe...
Qiong Cheng, Piotr Berman, Robert W. Harrison, Ale...
BIBM
2008
IEEE
144views Bioinformatics» more  BIBM 2008»
14 years 6 months ago
PhyQL: A Web-Based Phylogenetic Visual Query Engine
Biologists are often interested to query published phylogenetic data for research purposes. PhyQL, a web-based visual phylogenetic query engine, can be quite useful on this regard...
Shahriyar Hossain, Munirul Islam, Jesmin, Hasan M....