This paper presents results from an ongoing effort in applying a variety of induction-based methods to the problem of predicting the biological activity of noncongeneric (structu...
A Bayesian method for estimating the amino acid distributions in the states of a hidden Markov model (HMM) for a protein familyor the columns of a multiple alignment of that famil...
Michael Brown, Richard Hughey, Anders Krogh, I. Sa...
Algorithmsbasedonprobability theorycanaddressissues of uncertainty directly throughtheir representational frameworkandtheir theoryfor data combination.In this paper, wediscuss the...
Wedescribe various methods designed to discover knowledge in the GenBanknucleic acid sequence database. Using a grammatical model of gene structure, we create a parse tree of a ge...
Jeffery S. Aaronson, Juergen Haas, G. Christian Ov...
There are several dimensions and levels of complexity in which information on protein motifs may be available. For example, onedimensional sequence motifs may be associated with s...
Darrell Conklin, Suzanne Fortier, Janice I. Glasgo...
Thoughit has been possible in the past to learn to predict DNAhydration patterns from crystallographic data, there is ambiguity in the choice of training data (both in terms of th...
Dawn M. Cohen, Casimir A. Kulikowski, Helen Berman
A new version of the GRAIL system (Uberbacher and Mural, 1991; Mural et al., 1992; Uberbacher et al., 1993), called GRAILII, has recently been developed (Xu et al., 1994). GRAILII...
Yin Xu, J. Ralph Einstein, Richard J. Mural, Manes...
Weconsider the problem of parsing a sequence into different classes of subsequences.Twocommonexamplesare finding the exons and introns in genomicsequences and identifying the seco...
Wepresent the prototype of a software system, cMledGeneQuiz,for large-scale biological sequence analysis. The system was designed to meet the needs that arise in computational seq...
Michael Scharf, Reinhard Schneider, Georg Casari, ...