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ISMB
1994
13 years 10 months ago
Evolution of a Computer Program for Classifying Protein Segments as Transmembrane Domains Using Genetic Programming
The recently-developedgenetic programming paradigmisused to evoIve a computer program to classify a given protein segment as being a transmembrane domainor non-uansmembranearea of...
John R. Koza
ISMB
1994
13 years 10 months ago
Discovering Side-Chain Correlations In alpha-Helices
Tod M. Klingler, Douglas L. Brutlag
ISMB
1994
13 years 10 months ago
Toward Unification of Taxonomy Databases in a Distributed Environment
Hajime Kitakami, Yoshio Tateno, Takashi Gojobori
ISMB
1994
13 years 10 months ago
Inductive Logic Programming Used to Discover Topological Constraints in Protein Structures
Thispaperdescribesthe applicationof the Inductive Logic Programming0LP) program GOLEMto the discoveryof constraintsin the packingof beta-sheets in alpha/betaproteins. Theseconstra...
Ross D. King, Dominic A. Clark, Jack Shirazi, Mich...
ISMB
1994
13 years 10 months ago
An Efficient Method for Multiple Sequence Alignment
Multiple sequence alignment has been a useful methodin the study of molecular evolution and sequence-structure relationships. This paper presents a newmethodfor multiple sequence ...
Jin Kim, Sakti Pramanik
ISMB
1994
13 years 10 months ago
Representations of Metabolic Knowledge: Pathways
The automatic generation of drawings of metabolic pathways is a challenging problem that depends intimately on exactly what information has been recorded for each pathway, and on ...
Peter D. Karp, Suzanne M. Paley
ISMB
1994
13 years 10 months ago
Stochastic Motif Extraction Using Hidden Markov Model
In this paper, westudy the application of an ttMM(hidden Markov model) to the problem of representing protein sequencesby a stochastic motif. Astochastic protein motif represents ...
Yukiko Fujiwara, Minoru Asogawa, Akihiko Konagaya
ISMB
1994
13 years 10 months ago
Aligning Genomes with Inversions and Swaps
J. L. Holloway, Paul Cull
ISMB
1994
13 years 10 months ago
Neural Networks for Determining Protein Specificity and Multiple Alignment of Binding Sites
Weuse a quantitative definition of specificity to developa neural networkfor the identification of commonprotein binding sites in a collection of unaligned DNAfragments. Wedemonst...
John M. Heumann, Alan S. Lapedes, Gary D. Stormo