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RECOMB
2005
Springer
14 years 12 months ago
Consensus Folding of Unaligned RNA Sequences Revisited
As one of the earliest problems in computational biology, RNA secondary structure prediction (sometimes referred to as "RNA folding") problem has attracted attention agai...
Vineet Bafna, Haixu Tang, Shaojie Zhang
RECOMB
2005
Springer
14 years 12 months ago
Improved Recombination Lower Bounds for Haplotype Data
Recombination is an important evolutionary mechanism responsible for the genetic diversity in humans and other organisms. Recently, there has been extensive research on understandi...
Vineet Bafna, Vikas Bansal
RECOMB
2005
Springer
14 years 12 months ago
Information Theoretic Approaches to Whole Genome Phylogenies
We describe a novel method for efficient reconstruction of phylogenetic trees, based on sequences of whole genomes or proteomes, whose lengths may greatly vary. The core of our me...
David Burstein, Igor Ulitsky, Tamir Tuller, Benny ...
RECOMB
2005
Springer
14 years 12 months ago
RNA-RNA Interaction Prediction and Antisense RNA Target Search
Abstract. Recent studies demonstrating the existence of special non-coding "antisense" RNAs used in post-transcriptional gene regulation have received considerable attent...
Can Alkan, Emre Karakoç, Joseph H. Nadeau, ...
RECOMB
2005
Springer
14 years 12 months ago
A Framework for Orthology Assignment from Gene Rearrangement Data
Abstract. Gene rearrangements have been used successfully in phylogenetic reconstruction and comparative genomics, but usually under the assumption that all genomes have the same g...
Krister M. Swenson, Nicholas D. Pattengale, Bernar...
RECOMB
2005
Springer
14 years 12 months ago
Very Low Power to Detect Asymmetric Divergence of Duplicated Genes
Abstract. Asymmetric functional divergence of paralogues is a key aspect of the traditional model of evolution following duplication. If one gene continues to perform the ancestral...
Cathal Seoighe, Konrad Scheffler
RECOMB
2005
Springer
14 years 12 months ago
Reversals of Fortune
Abstract. The objective function of the genome rearrangement problems allows the integration of other genome-level problems so that they may be solved simultaneously. Three example...
David Sankoff, Chunfang Zheng, Aleksander Lenert
RECOMB
2005
Springer
14 years 12 months ago
Power Boosts for Cluster Tests
Abstract. Gene cluster significance tests that are based on the number of genes in a cluster in two genomes, and how compactly they are distributed, but not their order, may be mad...
David Sankoff, Lani Haque
RECOMB
2005
Springer
14 years 12 months ago
Individual Gene Cluster Statistics in Noisy Maps
Abstract. Identification of homologous chromosomal regions is important for understanding evolutionary processes that shape genome evolution, such as genome rearrangements and larg...
Narayanan Raghupathy, Dannie Durand
RECOMB
2005
Springer
14 years 12 months ago
A Partial Solution to the C-Value Paradox
In the half-century since the C-value paradox (the apparent lack of correlation between organismal genome size and morphological complexity) was described, there have been no expli...
Jeffrey M. Marcus