Sciweavers

RECOMB
2006
Springer
14 years 12 months ago
Genome-Wide Discovery of Modulators of Transcriptional Interactions in Human B Lymphocytes
Abstract. Transcriptional interactions in a cell are modulated by a variety of mechanisms that prevent their representation as pure pairwise interactions between a transcription fa...
Kai Wang, Ilya Nemenman, Nilanjana Banerjee, Adam ...
RECOMB
2006
Springer
14 years 12 months ago
Simulating Protein Motions with Rigidity Analysis
Abstract. Protein motions, ranging from molecular flexibility to largescale conformational change, play an essential role in many biochemical processes. Despite the explosion in ou...
Shawna L. Thomas, Xinyu Tang, Lydia Tapia, Nancy M...
RECOMB
2006
Springer
14 years 12 months ago
Integrated Protein Interaction Networks for 11 Microbes
We have combined four different types of functional genomic data to create high coverage protein interaction networks for 11 microbes. Our integration algorithm naturally handles s...
Balaji S. Srinivasan, Antal F. Novak, Jason Flanni...
RECOMB
2006
Springer
14 years 12 months ago
New Methods for Detecting Lineage-Specific Selection
Abstract. So far, most methods for identifying sequences under selection based on comparative sequence data have either assumed selectional pressures are the same across all branch...
Adam C. Siepel, Katherine S. Pollard, David Haussl...
RECOMB
2006
Springer
14 years 12 months ago
Algorithms to Distinguish the Role of Gene-Conversion from Single-Crossover Recombination in the Derivation of SNP Sequences in
Meiotic recombination is a fundamental biological event and one of the principal evolutionary forces responsible for shaping genetic variation within species. In addition to its fu...
Yun S. Song, Zhihong Ding, Dan Gusfield, Charles H...
RECOMB
2006
Springer
14 years 12 months ago
Phylogenetic Profiling of Insertions and Deletions in Vertebrate Genomes
Micro-indels are small insertion or deletion events (indels) that occur during genome evolution. The study of micro-indels is important, both in order to better understand the unde...
Sagi Snir, Lior Pachter
RECOMB
2006
Springer
14 years 12 months ago
Permutation Filtering: A Novel Concept for Significance Analysis of Large-Scale Genomic Data
Permutation of class labels is a common approach to build null distributions for significance analyis of microarray data. It is assumed to produce random score distributions, which...
Stefanie Scheid, Rainer Spang
RECOMB
2006
Springer
14 years 12 months ago
A Sublinear-Time Randomized Approximation Scheme for the Robinson-Foulds Metric
The Robinson-Foulds (RF) metric is the measure most widely used in comparing phylogenetic trees; it can be computed in linear time using Day's algorithm. When faced with the n...
Nicholas D. Pattengale, Bernard M. E. Moret
RECOMB
2006
Springer
14 years 12 months ago
Alignment Statistics for Long-Range Correlated Genomic Sequences
It is well known that the base composition along eukaryotic genomes is long-range correlated. Here, we investigate the effect of such long-range correlations on alignment score sta...
Philipp W. Messer, Ralf Bundschuh, Martin Vingron,...
RECOMB
2006
Springer
14 years 12 months ago
Improving Prediction of Zinc Binding Sites by Modeling the Linkage Between Residues Close in Sequence
Abstract. We describe and empirically evaluate machine learning methods for the prediction of zinc binding sites from protein sequences. We start by observing that a data set consi...
Sauro Menchetti, Andrea Passerini, Paolo Frasconi,...