Protein structure prediction is considered to be the holy grail of bioinformatics. Ab initio and homology modelling are two important groups of methods used in protein structure p...
In recent microarray experiments thousands of gene expressions are simultaneously tested in comparing samples (e.g., tissue types or experimental conditions). Application of a sta...
In this study we have designed a novel algorithm for searching common segments in multiple DNA sequences. To improve efficiency in pattern searching, combination of hashing encodi...
Tun-Wen Pai, Margaret Dah-Tsyr Chang, Jia-Han Chu,...
Quantitative simultaneous monitoring of the expression levels of thousands of genes under various experimental conditions is now possible using microarray experiments. The resulti...
Biopathway databases have been developed, such as KEGG and EcoCyc, that compile interaction structures of biopathways together with biological annotations. However, these biopathw...
Mutation in HIV-1 is extremely rapid, a consequence of a low-fidelity viral reverse transcription process. The envelope gene has been shown to accumulate substitutions at a rate o...
Fast, accurate, and scalable search techniques for homology searching of large genomic collections are becoming an increasingly important requirement as genomic sequence collectio...
Undiscovered relationships in a data set may confound analyses, particularly those that assume data independence. Such problems occur when characters used for phylogenetic analyse...
Anne M. Maglia, Jennifer L. Leopold, Venkat Ram Gh...