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BMCBI
2011
13 years 6 months ago
A theoretical entropy score as a single value to express inhibitor selectivity
Background: Designing maximally selective ligands that act on individual targets is the dominant paradigm in drug discovery. Poor selectivity can underlie toxicity and side effect...
Joost C. M. Uitdehaag, Guido J. R. Zaman
BMCBI
2011
13 years 6 months ago
Analysis on the reconstruction accuracy of the Fitch method for inferring ancestral states
Background: As one of the most widely used parsimony methods for ancestral reconstruction, the Fitch method minimizes the total number of hypothetical substitutions along all bran...
Jialiang Yang, Jun Li, Liuhuan Dong, Stefan Gr&uum...
BIOINFORMATICS
2011
13 years 6 months ago
All-atom knowledge-based potential for RNA structure prediction and assessment
Motivation: Over the recent years, the vision that RNA simply serves as information transfer molecule has dramatically changed. The study of the sequence/structure/function relati...
Emidio Capriotti, Tomás Norambuena, Marc A....
VC
2010
179views more  VC 2010»
13 years 6 months ago
A comparative study of existing metrics for 3D-mesh segmentation evaluation
Halim Benhabiles, Jean-Philippe Vandeborre, Guilla...
VC
2010
124views more  VC 2010»
13 years 6 months ago
Segmenting point-sampled surfaces
Ichitaro Yamazaki, Vijay Natarajan, Zhaojun Bai, B...
VC
2010
212views more  VC 2010»
13 years 6 months ago
Interactive evolutionary 3D fractal modeling
In this research we present a technique for the automatic generation of 3D art form, which allows designers to get access to large number of 3D shapes that can be altered interact...
Wenjun Pang, K. C. Hui
VC
2010
180views more  VC 2010»
13 years 6 months ago
SkelTre - Robust skeleton extraction from imperfect point clouds
Alexander Bucksch, Roderik C. Lindenbergh, Massimo...
VC
2010
168views more  VC 2010»
13 years 6 months ago
From sentence to emotion: a real-time three-dimensional graphics metaphor of emotions extracted from text
This paper presents a novel concept: a graphical representation of human emotion extracted from text sentences. The major contributions of this paper are the following. First, we p...
Stéphane Gobron, Junghyun Ahn, Georgios Pal...