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BIOCOMP
2008
14 years 1 months ago
Specificity Normalization for Identifying Selective Inhibitors in Virtual Screening
ct The enrichment and recall of known inhibitors in a virtual screen are correlated with the probability of finding effective inhibitors through this process. In practice, a large ...
Reetal Pai, James C. Sacchettini, Thomas R. Ioerge...
BIOCOMP
2008
14 years 1 months ago
GIPSCo: A Method for Comparison of Protein Structures Based on Geometric Invariants
Protein structure comparison is important for elucidation of evolutionary relationships, function and functionally important amino acid residues. We propose Geometric Invariant bas...
Sandeep Deshmukh, Aniket Dalal, Pramod Wangikar
BIOCOMP
2008
14 years 1 months ago
On the Role of a Nonlinear Stress-Strain Relation in Brain Trauma
We investigate how a nonlinear stress-strain relation (that leads to a stiffening of the brain matter under strain) influences the brain dynamics in traumatic situations. We numeri...
Igor Szczyrba, Martin Burtscher, Rafal Szczyrba
BIOCOMP
2008
14 years 1 months ago
Bioinformatics Tools: Searching for Markers in DNA/RNA Sequences
Research in bioinformatics and computational biology relies heavily on algorithms that facilitate the understanding of biological processes through the application of statistical ...
Kuha Mahalingam, Omar Bagasra
BIOCOMP
2008
14 years 1 months ago
Semantic Discovery of Protein Web Services
- Integrating information about protein sequence and structure allows further exploration and establishment of protein sequence-structure-function relations. However, protein data ...
Xiong Liu, Hassan A. Karimi
BIOCOMP
2008
14 years 1 months ago
Incomparability of Results Between Phylogenetic Search Programs
Kenneth Sundberg, Hyrum Carroll, Quinn Snell, Mark...