BMCBI
2007
14 years 14 days ago
2007
Background: An accurate description of protein shape derived from protein structure is necessary to establish an understanding of protein-ligand interactions, which in turn will l...
BMCBI
2007
14 years 14 days ago
2007
nd: A key abstraction in representing proteomics knowledge is the notion of unique identifiers for individual entities (e.g. proteins) and the massive graph of relationships among...
BMCBI
2007
14 years 14 days ago
2007
Considering that 80 genomes have been sequenced, providing us with the static information of the genome, it is still a long way to reveal the relationship between complex genotype...
BMCBI
2007
14 years 14 days ago
2007
Background: Identification of protein interacting sites is an important task in computational molecular biology. As more and more protein sequences are deposited without available...
BMCBI
2007
14 years 14 days ago
2007
Background: Many important high throughput projects use in situ hybridization and may require the analysis of images of spatial cross sections of organisms taken with cellular lev...
BMCBI
2007
14 years 14 days ago
2007
Background: Recent advances in Web and information technologies with the increasing decentralization of organizational structures have resulted in massive amounts of information r...
BMCBI
2007
14 years 14 days ago
2007
Background: When proteins are subjected to proteolytic digestion and analyzed by mass spectrometry using a method such as 2D LC MS/MS, only a portion of the proteotypic peptides a...
BMCBI
2007
14 years 14 days ago
2007
Background: Features of a DNA sequence can be found by compressing the sequence under a suitable model; good compression implies low information content. Good DNA compression mode...
BMCBI
2007
14 years 14 days ago
2007
Background: Recent development of mass spectrometry technology enabled the analysis of complex peptide mixtures. A lot of effort is currently devoted to the identification of biom...
BMCBI
2007
14 years 14 days ago
2007
Over the last two decades a large number of algorithms has been developed for regulatory motif finding. Here we show how many of these algorithms, especially those that model bind...