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BMCBI
2008
112views more  BMCBI 2008»
13 years 11 months ago
Predicting the Interactome of Xanthomonas oryzae pathovar oryzae for target selection and DB service
Background: Protein-protein interactions (PPIs) play key roles in various cellular functions. In addition, some critical inter-species interactions such as host-pathogen interacti...
Jeong-Gu Kim, Daeui Park, Byoung-Chul Kim, Seong-W...
BMCBI
2008
145views more  BMCBI 2008»
13 years 11 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
BMCBI
2008
63views more  BMCBI 2008»
13 years 11 months ago
SQUAT: A web tool to mine human, murine and avian SAGE data
Johan Leyritz, Stéphane Schicklin, Sylvain ...
BMCBI
2008
102views more  BMCBI 2008»
13 years 11 months ago
Significance analysis of microarray for relative quantitation of LC/MS data in proteomics
Background: Although fold change is a commonly used criterion in quantitative proteomics for differentiating regulated proteins, it does not provide an estimation of false positiv...
Bryan A. P. Roxas, Qingbo Li
BMCBI
2008
73views more  BMCBI 2008»
13 years 11 months ago
PhySIC_IST: cleaning source trees to infer more informative supertrees
Celine Scornavacca, Vincent Berry, Vincent Lefort,...
BMCBI
2008
130views more  BMCBI 2008»
13 years 11 months ago
A database of phylogenetically atypical genes in archaeal and bacterial genomes, identified using the DarkHorse algorithm
Background: The process of horizontal gene transfer (HGT) is believed to be widespread in Bacteria and Archaea, but little comparative data is available addressing its occurrence ...
Sheila Podell, Terry Gaasterland, Eric E. Allen
BMCBI
2008
186views more  BMCBI 2008»
13 years 11 months ago
Variable selection for large p small n regression models with incomplete data: Mapping QTL with epistases
Background: Identifying quantitative trait loci (QTL) for both additive and epistatic effects raises the statistical issue of selecting variables from a large number of candidates...
Min Zhang, Dabao Zhang, Martin T. Wells
BMCBI
2008
162views more  BMCBI 2008»
13 years 11 months ago
Improved identification of conserved cassette exons using Bayesian networks
Background: Alternative splicing is a major contributor to the diversity of eukaryotic transcriptomes and proteomes. Currently, large scale detection of alternative splicing using...
Rileen Sinha, Michael Hiller, Rainer Pudimat, Ulri...
BMCBI
2008
179views more  BMCBI 2008»
13 years 11 months ago
Building pathway clusters from Random Forests classification using class votes
Background: Recent years have seen the development of various pathway-based methods for the analysis of microarray gene expression data. These approaches have the potential to bri...
Herbert Pang, Hongyu Zhao
BMCBI
2008
129views more  BMCBI 2008»
13 years 11 months ago
A unified approach to false discovery rate estimation
Background: False discovery rate (FDR) methods play an important role in analyzing highdimensional data. There are two types of FDR, tail area-based FDR and local FDR, as well as ...
Korbinian Strimmer