BMCBI
2008
13 years 11 months ago
2008
Background: The integration of biomedical information is essential for tackling medical problems. We describe a data model in the domain of flow cytometry (FC) allowing for massiv...
BMCBI
2008
13 years 11 months ago
2008
Background: In metagenomic studies, a process called binning is necessary to assign contigs that belong to multiple species to their respective phylogenetic groups. Most of the cu...
BMCBI
2008
2008
Relating gene expression data on two-component systems to functional annotations in Escherichia coli
13 years 11 months ago
Background: Obtaining physiological insights from microarray experiments requires computational techniques that relate gene expression data to functional information. Traditionall...
BMCBI
2008
13 years 11 months ago
2008
Background: The evaluation of information retrieval techniques has traditionally relied on human judges to determine which documents are relevant to a query and which are not. Thi...
BMCBI
2008
13 years 11 months ago
2008
Background: The availability of various high-throughput experimental and computational methods allows biologists to rapidly infer functional relationships between genes. It is oft...
BMCBI
2008
13 years 11 months ago
2008
Background: The functional characterization of newly discovered proteins has been a challenge in the post-genomic era. Protein-protein interactions provide insights into the funct...
BMCBI
2008
13 years 11 months ago
2008
Background: Occult organizational structures in DNA sequences may hold the key to understanding functional and evolutionary aspects of the DNA molecule. Such structures can also p...
BMCBI
2008
13 years 11 months ago
2008
Background: Applications of computational methods for predicting protein functional linkages are increasing. In recent years, several bacteria-specific methods for predicting link...
BMCBI
2008
13 years 11 months ago
2008
Background: Biologically active sequence motifs often have positional preferences with respect to a genomic landmark. For example, many known transcription factor binding sites (T...
BMCBI
2008
13 years 11 months ago
2008
Background: FCI is an R code for analyzing data from real-time PCR experiments. This algorithm estimates standard curve features as well as nucleic acid concentrations and confide...