BMCBI
2010
13 years 11 months ago
2010
Background: Many structural properties such as solvent accessibility, dihedral angles and helix-helix contacts can be assigned to each residue in a membrane protein. Independent s...
BMCBI
2010
13 years 11 months ago
2010
Background: Robust biomarkers are needed to improve microbial identification and diagnostics. Proteomics methods based on mass spectrometry can be used for the discovery of novel ...
BMCBI
2010
13 years 11 months ago
2010
Background: Most software packages for whole genome association studies are non-graphical, purely text based programs originally designed to run with UNIX-like operating systems. ...
BMCBI
2010
13 years 11 months ago
2010
Background: Quantitative trait locus (QTL) mapping identifies genomic regions that likely contain genes regulating a quantitative trait. However, QTL regions may encompass tens to...
BMCBI
2010
13 years 11 months ago
2010
Background: Microarray data discretization is a basic preprocess for many algorithms of gene regulatory network inference. Some common discretization methods in informatics are us...
BMCBI
2010
13 years 11 months ago
2010
Background: High-throughput shotgun proteomics data contain a significant number of spectra from non-peptide ions or spectra of too poor quality to obtain highly confident peptide...
BMCBI
2010
13 years 11 months ago
2010
Background: In a time-course microarray experiment, the expression level for each gene is observed across a number of time-points in order to characterize the temporal trajectorie...
BMCBI
2010
13 years 11 months ago
2010
Background: Establishing the relationship between an organism's genome sequence and its phenotype is a fundamental challenge that remains largely unsolved. Accurately predict...
BMCBI
2010
13 years 11 months ago
2010
Background: Most biomedical ontologies are represented in the OBO Flatfile Format, which is an easy-to-use
BMCBI
2010
13 years 11 months ago
2010
Background: Most known eukaryotic genomes contain mobile copied elements called transposable elements. In some species, these elements account for the majority of the genome seque...