BMCBI
2010
13 years 11 months ago
2010
Background: Assembling genomic sequences from a set of overlapping reads is one of the most fundamental problems in computational biology. Algorithms addressing the assembly probl...
BMCBI
2010
13 years 11 months ago
2010
Background: The amount of available biological information is rapidly increasing and the focus of biological research has moved from single components to networks and even larger ...
BMCBI
2010
13 years 11 months ago
2010
Background: The study of protein-small molecule interactions is vital for understanding protein function and for practical applications in drug discovery. To benefit from the rapi...
BMCBI
2010
13 years 11 months ago
2010
BMCBI
2010
13 years 11 months ago
2010
Background: Failure on Highly Active Anti-Retroviral Treatment is often accompanied with development of antiviral resistance to one or more drugs included in the treatment. In gen...
BMCBI
2010
13 years 11 months ago
2010
Background: The binding of peptide fragments of antigens to class II MHC is a crucial step in initiating a helper T cell immune response. The identification of such peptide epitop...
BMCBI
2010
13 years 11 months ago
2010
Background: Protein conformation and protein/protein interaction can be elucidated by solution-phase Hydrogen/ Deuterium exchange (sHDX) coupled to high-resolution mass analysis o...
BMCBI
2010
13 years 11 months ago
2010
Background: Complexity and noise in expression quantitative trait loci (eQTL) studies make it difficult to distinguish potential regulatory relationships among the many interactio...
BMCBI
2010
13 years 11 months ago
2010
BMCBI
2010
13 years 11 months ago
2010
Background: There is a vast need to find clinically applicable protein biomarkers as support in cancer diagnosis and tumour classification. In proteomics research, a number of met...