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BMCBI
2010
133views more  BMCBI 2010»
13 years 11 months ago
Learning an enriched representation from unlabeled data for protein-protein interaction extraction
Background: Extracting protein-protein interactions from biomedical literature is an important task in biomedical text mining. Supervised machine learning methods have been used w...
Yanpeng Li, Xiaohua Hu, Hongfei Lin, Zhihao Yang
BMCBI
2010
134views more  BMCBI 2010»
13 years 11 months ago
BayesMotif: de novo protein sorting motif discovery from impure datasets
Background: Protein sorting is the process that newly synthesized proteins are transported to their target locations within or outside of the cell. This process is precisely regul...
Jianjun Hu, Fan Zhang
BMCBI
2010
148views more  BMCBI 2010»
13 years 11 months ago
Analysis of interactions between ribosomal proteins and RNA structural motifs
Background: One important goal of structural bioinformatics is to recognize and predict the interactions between protein binding sites and RNA. Recently, a comprehensive analysis ...
Giovanni Ciriello, Claudio Gallina, Concettina Gue...
BMCBI
2010
99views more  BMCBI 2010»
13 years 11 months ago
Prediction of novel precursor miRNAs using a context-sensitive hidden Markov model (CSHMM)
Background: It has been apparent in the last few years that small non coding RNAs (ncRNA) play a very significant role in biological regulation. Among these microRNAs (miRNAs), 22...
Sumeet Agarwal, Candida Vaz, Alok Bhattacharya, As...
BMCBI
2010
113views more  BMCBI 2010»
13 years 11 months ago
Prediction of FAD interacting residues in a protein from its primary sequence using evolutionary information
Background: Flavin binding proteins (FBP) plays a critical role in several biological functions such as electron transport system (ETS). These flavoproteins contain very tightly b...
Nitish K. Mishra, Gajendra P. S. Raghava
BMCBI
2010
158views more  BMCBI 2010»
13 years 11 months ago
A Bayesian network approach to feature selection in mass spectrometry data
Background: Time-of-flight mass spectrometry (TOF-MS) has the potential to provide non-invasive, high-throughput screening for cancers and other serious diseases via detection of ...
Karl W. Kuschner, Dariya I. Malyarenko, William E....
BMCBI
2010
142views more  BMCBI 2010»
13 years 11 months ago
Classification of protein sequences by means of irredundant patterns
Background: The classification of protein sequences using string algorithms provides valuable insights for protein function prediction. Several methods, based on a variety of diff...
Matteo Comin, Davide Verzotto
BMCBI
2010
106views more  BMCBI 2010»
13 years 11 months ago
A novel approach for haplotype-based association analysis using family data
Background: Haplotype-based approaches have been extensively studied for case-control association mapping in recent years. It has been shown that haplotype methods can provide mor...
Yixuan Chen, Xin Li, Jing Li