BMCBI
2010
13 years 11 months ago
2010
Background: Understanding of secondary metabolic pathway in plant is essential for finding druggable candidate enzymes. However, there are many enzymes whose functions are not yet...
BMCBI
2010
13 years 11 months ago
2010
Background: The protein folding problem remains one of the most challenging open problems in computational biology. Simplified models in terms of lattice structure and energy func...
BMCBI
2010
13 years 11 months ago
2010
Background: Protein-protein interactions play a key role in biological processes of proteins within a cell. Recent high-throughput techniques have generated protein-protein intera...
BMCBI
2010
13 years 11 months ago
2010
Background: This paper compares the most common digital signal processing methods of exon prediction in eukaryotes, and also proposes a technique for noise suppression in exon pre...
BMCBI
2010
13 years 11 months ago
2010
Background: Proteins show a great variety of 3D conformations, which can be used to infer their evolutionary relationship and to classify them into more general groups; therefore ...
BMCBI
2010
13 years 11 months ago
2010
Background: As the size of the known human interactome grows, biologists increasingly rely on computational tools to identify patterns that represent protein complexes and pathway...
BMCBI
2010
13 years 11 months ago
2010
Background: Folding of a protein into its three dimensional structure is influenced by both local and global interactions within a protein. Higher order residue interactions, like...
BMCBI
2010
13 years 11 months ago
2010
Background: MapReduce is a parallel framework that has been used effectively to design largescale parallel applications for large computing clusters. In this paper, we evaluate th...
BMCBI
2010
13 years 11 months ago
2010
Background: Protein structure comparison is a fundamental task in structural biology. While the number of known protein structures has grown rapidly over the last decade, searchin...
BMCBI
2010
13 years 11 months ago
2010
Background: Increasing amount of data from comparative genomics, and newly developed technologies producing accurate gene expression data facilitate the study of the expression di...