BMCBI
2010
13 years 11 months ago
2010
Background: Position-specific priors have been shown to be a flexible and elegant way to extend the power of Gibbs sampler-based motif discovery algorithms. Information of many ty...
BMCBI
2010
13 years 11 months ago
2010
Background: In cancer, gene networks and pathways often exhibit dynamic behavior, particularly during the process of carcinogenesis. Thus, it is important to prioritize those gene...
BMCBI
2010
13 years 11 months ago
2010
Background: Detection of common evolutionary origin (homology) is a primary means of inferring protein structure and function. At present, comparison of protein families represent...
BMCBI
2010
13 years 11 months ago
2010
Background: For ecological studies, it is crucial to count on adequate descriptions of the environments and samples being studied. Such a description must be done in terms of thei...
BMCBI
2010
13 years 11 months ago
2010
Background: Guanosine triphosphate (GTP)-binding proteins play an important role in regulation of G-protein. Thus prediction of GTP interacting residues in a protein is one of the...
BMCBI
2010
13 years 11 months ago
2010
Background: Ortholog detection methods present a powerful approach for finding genes that participate in similar biological processes across different organisms, extending our und...
BMCBI
2010
13 years 11 months ago
2010
Background: Advances in biotechnology and in high-throughput methods for gene analysis have contributed to an exponential increase in the number of scientific publications in thes...
BMCBI
2010
13 years 11 months ago
2010
Background: The development and simulation of dynamic models of terpenoid biosynthesis has yielded a systems perspective that provides new insights into how the structure of this ...
BMCBI
2010
13 years 11 months ago
2010
Background: The binding of peptide fragments of extracellular peptides to class II MHC is a crucial event in the adaptive immune response. Each MHC allotype generally binds a dist...
BMCBI
2010
13 years 11 months ago
2010
Background: The prediction of protein-protein interactions is an important step toward the elucidation of protein functions and the understanding of the molecular mechanisms insid...