BMCBI
2011
13 years 6 months ago
2011
Background: As one of the most widely used parsimony methods for ancestral reconstruction, the Fitch method minimizes the total number of hypothetical substitutions along all bran...
BMCBI
2011
13 years 6 months ago
2011
Background: The Cancer Genome Anatomy Project (CGAP) xProfiler and cDNA Digital Gene Expression Displayer (DGED) have been made available to the scientific community over a decade...
BMCBI
2011
13 years 6 months ago
2011
BMCBI
2011
13 years 6 months ago
2011
Background: When investigating covariate interactions and group associations with standard regression analyses, the relationship between the response variable and exposure may be ...
BMCBI
2011
13 years 6 months ago
2011
Background: The way mechanical stress is distributed inside and propagated by proteins and other biopolymers largely defines their function. Yet, determining the network of intera...
BMCBI
2011
13 years 6 months ago
2011
Background: It is difficult to accurately interpret chromosomal correspondences such as true orthology and paralogy due to significant divergence of genomes from a common ancestor...
BMCBI
2011
13 years 6 months ago
2011
Background: In the last decades, microarray technology has spread, leading to a dramatic increase of publicly available datasets. The first statistical tools developed were focuse...
BMCBI
2011
13 years 6 months ago
2011
Background: Methods of determining whether or not any particular HIV-1 sequence stems - completely or in part - from some unknown HIV-1 subtype are important for the design of vac...
BMCBI
2011
13 years 6 months ago
2011
Background: Viral zoonosis, the transmission of a virus from its primary vertebrate reservoir species to humans, requires ubiquitous cellular proteins known as receptor proteins. ...
BMCBI
2011
13 years 6 months ago
2011
Background: Microarrays offer great potential as a platform for molecular diagnostics, testing clinical samples for the presence of numerous biomarkers in highly multiplexed assay...