Since the discovery of the "Philadelphia chromosome" in chronic myelogenous leukemia in 1960, there is an ongoing intensive research of chromosomal aberrations in cancer....
We study the problem of transforming a multichromosomal genome into another using Double-Cut-and-Join (DCJ) operations. We introduce the notion of DCJ scenario that does not break ...
Abstract. Contemporary inferences about evolution occasionally involve analyzing infinitely large feature spaces, requiring specific algorithmic techniques. We consider parsimony a...
In the past years, many combinatorial arguments have been made to support the theory that mammalian genome rearrangement scenarios rely heavily on breakpoint reuse. Different model...
Abstract. As data about genomic architecture accumulates, genomic rearrangements have attracted increasing attention. One of the main rearrangement mechanisms, inversions (also cal...
Krister M. Swenson, Yu Lin, Vaibhav Rajan, Bernard...
Abstract. Whole genome doubling (WGD), a frequent occurrence during the evolution of the angiopsperms, complicates ancestral gene order reconstruction due to the multiplicity of so...
David Sankoff, Chunfang Zheng, P. Kerr Wall, Claud...
Following various genetic mapping techniques conducted on different segregating populations, one or more genetic maps are obtained for a given species. However, recombination analy...
Abstract. One phylogeny-based approach to horizontal gene transfer (HGT) detection entails comparing the topology of a gene tree to that of the species tree, and using their differ...
We describe algorithms to explore the space of all possible reconciliations between a gene tree and a species tree. We propose an algorithm for generating a random reconciliation, ...