RECOMB
2007
Springer
15 years 22 days ago
2007
Springer
It is often impossible to sequence all descendent genomes to reconstruct an ancestral genome. In addition, more genomes do not necessarily give a higher accuracy for the reconstruc...
RECOMB
2007
Springer
15 years 22 days ago
2007
Springer
Learning the structure of a gene regulatory network from time-series gene expression data is a significant challenge. Most approaches proposed in the literature to date attempt to ...
RECOMB
2007
Springer
15 years 22 days ago
2007
Springer
The problem of Sorting signed permutations by reversals is a well studied problem in computational biology. The first polynomial time algorithm was presented by Hannenhalli and Pev...
RECOMB
2007
Springer
15 years 22 days ago
2007
Springer
In the past decade, genome rearrangements have attracted increasing attention from both biologists and computer scientists as a new type of data for phylogenetic analysis. Methods ...
RECOMB
2007
Springer
15 years 22 days ago
2007
Springer
Multi-break rearrangements break a genome into multiple fragments and further glue them together in a new order. While 2break rearrangements represent standard reversals, fusions, ...
RECOMB
2007
Springer
15 years 22 days ago
2007
Springer
Abstract. Side-chain prediction is an important subproblem of the general protein folding problem. Despite much progress in side-chain prediction, performance is far from satisfact...
RECOMB
2007
Springer
15 years 22 days ago
2007
Springer
Currently, large-scale projects are underway to perform whole genome disease association studies. Such studies involve the genotyping of hundreds of thousands of SNP markers. One o...
RECOMB
2007
Springer
15 years 22 days ago
2007
Springer
We describe an algorithm, IsoRank, for global alignment of two protein-protein interaction (PPI) networks. IsoRank aims to maximize the overall match between the two networks; in c...
RECOMB
2007
Springer
15 years 22 days ago
2007
Springer
Genetic instability represents an important type of biological markers for cancer and many other diseases. Array Comparative Genome Hybridization (aCGH) is a high-throughput cytoge...
RECOMB
2007
Springer
15 years 22 days ago
2007
Springer
Transcription factor (TF) binding to its DNA target site is a fundamental regulatory interaction. The most common model used to represent TF binding specificities is a position spe...