Protein sequence analysis is an important tool to decode the logic of life. One of the most important similarity measures in this area is the edit distance between amino acids of ...
This paper describes a new strategy for designing degenerate primers for a given multiple alignment of amino acid sequences. Degenerate primers are useful for amplifying homologou...
We have developed a novel algorithm for protein backbone structure determination using global orientational restraints on internuclear bond vectors derived from residual dipolar c...
Lincong Wang, Ramgopal R. Mettu, Ryan H. Lilien, B...
NMR resonance peak assignment is one of the key steps in solving an NMR protein structure. The assignment process links resonance peaks to individual residues of the target protei...
Xiang Wan, Dong Xu, Carolyn M. Slupsky, Guohui Lin
DNA microarray technology provides a broad snapshot of the state of the cell by measuring the expression levels of thousands of genes simultaneously. Visualization techniques can ...
Regulatory sequence elements provide important clues to understanding and predicting gene expression. Although the binding sites for hundreds of transcription factors are known, t...
Mihaela Zavolan, Nicholas D. Socci, Nikolaus Rajew...
This paper presents a novel algorithm for identification and functional characterization of “key” genome features responsible for a particular biochemical process of interest....
Gong-Xin Yu, George Ostrouchov, Al Geist, Nagiza F...
The problem addressed by this paper is accurate and automatic gene annotation following precise identification/annotation of exon and intron boundaries of biologically verified ...
Alexandre Tchourbanov, Daniel Quest, Hesham H. Ali...