Genomes to Life (GTL), the U.S. Department of Energy Office of Science’s systems biology program, focuses on environmental microbiology. Over the next 10 to 20 years, GTL’s ke...
Marvin Frazier, David Thomassen, Aristides Patrino...
We propose two methods for finding similarities in protein structure databases. Our techniques extract feature vectors on triplets of SSEs (Secondary Structure Elements) of prote...
Peptide-based vaccines, in which small peptides derived from target proteins (epitopes) are used to provoke an immune reaction, have attracted considerable attention recently as a...
Physical map reconstruction in the presence of errors is a central problem in genetics of high computational complexity. A parallel genetic algorithm for a maximum likelihood esti...
Suchendra M. Bhandarkar, Jinling Huang, Jonathan A...
We have constructed a computer model of the cytotoxic T lymphocyte (CTL) response to antigen and the maintenance of immunological memory. Because immune responses often begin with...
Dennis L. Chao, Miles P. Davenport, Stephanie Forr...
Reverse-engineering of gene networks using linear models often results in an underdetermined system because of excessive unknown parameters. In addition, the practical utility of ...