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CSB
2003
IEEE
14 years 4 months ago
LOGOS: a modular Bayesian model for de novo motif detection
The complexity of the global organization and internal structures of motifs in higher eukaryotic organisms raises significant challenges for motif detection techniques. To achiev...
Eric P. Xing, Wei Wu, Michael I. Jordan, Richard M...
CSB
2003
IEEE
14 years 4 months ago
Pathway Logic Modeling of Protein Functional Domains in Signal Transduction
Carolyn L. Talcott, Steven Eker, Merrill Knapp, Pa...
CSB
2003
IEEE
113views Bioinformatics» more  CSB 2003»
14 years 4 months ago
An Optimal DNA Segmentation Based on the MDL Principle
: The biological world is highly stochastic and inhomogeneous in its behaviour. There are regions in DNA with high concentration of G or C bases; stretches of sequences with an abu...
Wojciech Szpankowski, Wenhui Ren, Lukasz Szpankows...
CSB
2003
IEEE
14 years 4 months ago
Fast and Accurate Probe Selection Algorithm for Large Genomes
The oligo microarray (DNA chip) technology in recent years has a significant impact on genomic study. Many fields such as gene discovery, drug discovery, toxicological research ...
Wing-Kin Sung, Wah-Heng Lee
CSB
2003
IEEE
14 years 4 months ago
Genomic Sequence Analysis Using Gap Sequences and Pattern Filtering
A new pattern filtering technique is developed to analyze the genomic sequence in this research based on gap sequences, in which the distance of the same symbol is recorded consec...
Shih-Chieh Su, Chia H. Yeh, C. C. Jay Kuo
CSB
2003
IEEE
111views Bioinformatics» more  CSB 2003»
14 years 4 months ago
A Contradiction-Based Framework for Testing Gene Regulation Hypotheses
We have developed a mathematical framework for representing and testing hypotheses about gene, protein, and signaling molecule interactions. It takes a hierarchical, contradiction...
Steve Racunas, Nigam Shah, Nina V. Fedoroff
CSB
2003
IEEE
14 years 4 months ago
Estimating Recombination Rate Distribution by Optimal Quantization
We obtain recombination rate distribution functions for all human chromosomes using an optimal quantization method. This non-parametric method allows us to control over-/under-fi...
Mingzhou Song, Stéphane Boissinot, Robert M...
CSB
2003
IEEE
14 years 4 months ago
Fast and Sensitive Probe Selection for DNA Chips Using Jumps in Matching Statistics
The design of large scale DNA microarrays is a challenging problem. So far, probe selection algorithms must trade the ability to cope with large scale problems for a loss of accur...
Sven Rahmann
CSB
2003
IEEE
14 years 4 months ago
A Probabilistic Model for Identifying Protein Names and their Name Boundaries
This paper proposes a method for identifying protein names in biomedical texts with an emphasis on detecting protein name boundaries. We use a probabilistic model which exploits s...
Kazuhiro Seki, Javed Mostafa