A major challenge for genomewide disease association studies is the high cost of genotyping large number of single nucleotide polymorphisms (SNP). The correlations between SNPs, h...
Searching genomes for RNA secondary structure with computational methods has become an important approach to the annotation of non-coding RNAs. However, due to the lack of effici...
Yinglei Song, Chunmei Liu, Russell L. Malmberg, Fa...
This study is aimed at elucidating putative transcription regulators (TRs) responsible for the observed differential expression pattern. Combined direct promoter binding and indir...
Andrey Y. Sivachenko, Anton Yuryev, Nikolai Darase...
High-throughput methods for detecting protein-protein interactions (PPI) have given researchers an initial global picture of protein interactions on a genomic scale. The usefulnes...
Information technology research has played a significant role in the high-throughput acquisition and analysis of biological information. The tremendous amount of information gath...
Protein Data Integration approaches at the moment considers data sources as data repositories, but not as applications; which in turn may embody complex interactions with other da...
Amandeep S. Sidhu, Tharam S. Dillon, Elizabeth Cha...
In the initial stage of sequence analysis, a biologist is first faced with the questions about how to choose the best tool to align sequences of interest and how to analyze and v...
Arthur Chun-Chieh Shih, D. T. Lee, Laurent Lin, Ch...