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BMCBI
2010
119views more  BMCBI 2010»
14 years 6 days ago
A comparison of internal validation techniques for multifactor dimensionality reduction
Background: It is hypothesized that common, complex diseases may be due to complex interactions between genetic and environmental factors, which are difficult to detect in high-di...
Stacey J. Winham, Andrew J. Slater, Alison A. Mots...
BMCBI
2010
132views more  BMCBI 2010»
14 years 6 days ago
Protein network prediction and topological analysis in Leishmania major as a tool for drug target selection
Background: Leishmaniasis is a virulent parasitic infection that causes a worldwide disease burden. Most treatments have toxic side-effects and efficacy has decreased due to the e...
Andrés F. Flórez, Daeui Park, Jong B...
BMCBI
2008
114views more  BMCBI 2008»
14 years 6 days ago
Identifying a few foot-and-mouth disease virus signature nucleotide strings for computational genotyping
Background: Serotypes of the Foot-and-Mouth disease viruses (FMDVs) were generally determined by biological experiments. The computational genotyping is not well studied even with...
Guohui Lin, Zhipeng Cai, Junfeng Wu, Xiu-Feng Wan,...
BMCBI
2010
135views more  BMCBI 2010»
14 years 6 days ago
Detecting disease associated modules and prioritizing active genes based on high throughput data
Background: The accumulation of high-throughput data greatly promotes computational investigation of gene function in the context of complex biological systems. However, a biologi...
Yu-Qing Qiu, Shi-Hua Zhang, Xiang-Sun Zhang, Luona...
BMCBI
2010
86views more  BMCBI 2010»
14 years 6 days ago
A novel approach to simulate gene-environment interactions in complex diseases
Background: Complex diseases are multifactorial traits caused by both genetic and environmental factors. They represent the major part of human diseases and include those with lar...
Roberto Amato, Michele Pinelli, Daniel D'Andrea, G...
FLAIRS
2006
14 years 1 months ago
Cognitive Simulation in Virtual Patients
We present an overview of the Virtual Patient project at the University of Maryland, which is developing a cognitive model of humans experiencing various states of health and dise...
Sergei Nirenburg, Marjorie McShane, Stephen Beale,...
BIBE
2001
IEEE
14 years 3 months ago
Audio and Vision-Based Evaluation of Parkinson's Disease from Discourse Video
Parkinson's disease (PD) belongs to a class of neurodegenerative diseases that affect both the patient's speech and motor capabilities. To date, PD diagnosis and the det...
Francis K. H. Quek, Robert K. Bryll, Mary P. Harpe...
BIRTHDAY
2005
Springer
14 years 5 months ago
Still
Keywords Name of the disease and synonyms Definition/Diagnostic criteria Juvenile form Comments on the differential diagnosis Incidence Clinical description Method of biological d...
Alice ter Meulen