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BMCBI
2010
117views more  BMCBI 2010»
13 years 11 months ago
Extracting causal relations on HIV drug resistance from literature
Background: In HIV treatment it is critical to have up-to-date resistance data of applicable drugs since HIV has a very high rate of mutation. These data are made available throug...
Quoc-Chinh Bui, Breanndán Ó Nuall&aa...
RECOMB
2010
Springer
14 years 1 months ago
An Algorithmic Framework for Predicting Side-Effects of Drugs
Abstract. One of the critical stages in drug development is the identification of potential side effects for promising drug leads. Large scale clinical experiments aimed at discove...
Nir Atias, Roded Sharan
GECCO
2006
Springer
172views Optimization» more  GECCO 2006»
14 years 3 months ago
Multi-objective optimisation of the protein-ligand docking problem in drug discovery
The pharmaceutical industry is facing an ever-increasing demand to discover novel drugs that are more effective and safer than existing ones. The industry faces huge problem in im...
A. Oduguwa, A. Tiwari, S. Fiorentino, R. Roy
ECAI
2006
Springer
14 years 3 months ago
Abductive Logic Programming in the Clinical Management of HIV/AIDS
Abstract. This paper presents a new Abductive Logic Programming (ALP) approach for assisting clinicians in the selection of antiretroviral drugs for patients infected with Human Im...
Oliver Ray, Athos Antoniades, Antonis C. Kakas, Io...
GECCO
2005
Springer
154views Optimization» more  GECCO 2005»
14 years 5 months ago
The molecule evoluator: an interactive evolutionary algorithm for designing drug molecules
To help chemists design new drugs, we created a tool that uses interactive evolution to design drug molecules, the “Molecule Evoluator”. In contrast to most other evolutionary...
Eric-Wubbo Lameijer, Adriaan P. IJzerman, Joost N....