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BMCBI
2004
154views more  BMCBI 2004»
13 years 11 months ago
Computation of elementary modes: a unifying framework and the new binary approach
Background: Metabolic pathway analysis has been recognized as a central approach to the structural analysis of metabolic networks. The concept of elementary (flux) modes provides ...
Julien Gagneur, Steffen Klamt
JCB
2008
96views more  JCB 2008»
13 years 11 months ago
Computing Knock-Out Strategies in Metabolic Networks
Given a metabolic network in terms of its metabolites and reactions, our goal is to efficiently compute the minimal knock out sets of reactions required to block a given behaviour....
Utz-Uwe Haus, Steffen Klamt, Tamon Stephen
BMCBI
2006
107views more  BMCBI 2006»
13 years 11 months ago
Analysis of optimal phenotypic space using elementary modes as applied to Corynebacterium glutamicum
Background: Quantification of the metabolic network of an organism offers insights into possible ways of developing mutant strain for better productivity of an extracellular metab...
Kalyan Gayen, K. V. Venkatesh
BMCBI
2007
182views more  BMCBI 2007»
13 years 11 months ago
Hybrid elementary flux analysis/nonparametric modeling: application for bioprocess control
Background: The progress in the "-omic" sciences has allowed a deeper knowledge on many biological systems with industrial interest. This knowledge is still rarely used ...
Ana P. Teixeira, Carlos Alves, Paula M. Alves, Man...