Background: There are a number of methods (also called: measures) currently in use that quantify codon usage in genes. These measures are often influenced by other sequence proper...
Background: With microarray technology the expression of thousands of genes can be measured simultaneously. It is well known that the expression levels of genes of interacting pro...
The task of clustering is to identify classes of similar objects among a set of objects. The definition of similarity varies from one clustering model to another. However, in most ...
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
Background: The identification of differentially expressed genes (DEGs) from Affymetrix GeneChips arrays is currently done by first computing expression levels from the low-level ...
Background: With the development of DNA hybridization microarray technologies, nowadays it is possible to simultaneously assess the expression levels of thousands to tens of thous...
Background: Microarray data analysis is notorious for involving a huge number of genes compared to a relatively small number of samples. Gene selection is to detect the most signi...
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Magnus Rattray, Neil D. Lawrenc...
DNA microarrays are used to measure the expression levels of thousands of genes simultaneously. In a time series experiment, the gene expressions are measured as a function of tim...
Michel A. Westenberg, Sacha A. F. T. van Hijum, Os...
Background: Present-day `-omics' technologies produce overwhelming amounts of data which include genome sequences, information on gene expression (transcripts and proteins) a...
Maria Luisa Chiusano, Nunzio D'Agostino, Alessandr...