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BMCBI
2010
143views more  BMCBI 2010»
13 years 11 months ago
Learning gene regulatory networks from only positive and unlabeled data
Background: Recently, supervised learning methods have been exploited to reconstruct gene regulatory networks from gene expression data. The reconstruction of a network is modeled...
Luigi Cerulo, Charles Elkan, Michele Ceccarelli
BMCBI
2010
156views more  BMCBI 2010»
13 years 11 months ago
Global screening of potential Candida albicans biofilm-related transcription factors via network comparison
Background: Candida albicans is a commonly encountered fungal pathogen in humans. The formation of biofilm is a major virulence factor in C. albicans pathogenesis and is related t...
Yu-Chao Wang, Chung-Yu Lan, Wen-Ping Hsieh, Luis A...
BMCBI
2010
164views more  BMCBI 2010»
13 years 11 months ago
Gene regulatory networks modelling using a dynamic evolutionary hybrid
Background: Inference of gene regulatory networks is a key goal in the quest for understanding fundamental cellular processes and revealing underlying relations among genes. With ...
Ioannis A. Maraziotis, Andrei Dragomir, Dimitris T...
BIOCOMP
2006
14 years 25 days ago
Dynamic Bayesian Network (DBN) with Structure Expectation Maximization (SEM) for Modeling of Gene Network from Time Series Gene
Exploring gene regulatory network is a key topic in molecular biology. In this paper, we present a new dynamic Bayesian network (DBN) framework embedded with structural expectatio...
Yu Zhang, Zhidong Deng, Hongshan Jiang, Peifa Jia
GECCO
2006
Springer
220views Optimization» more  GECCO 2006»
14 years 3 months ago
Comparing evolutionary algorithms on the problem of network inference
In this paper, we address the problem of finding gene regulatory networks from experimental DNA microarray data. We focus on the evaluation of the performance of different evoluti...
Christian Spieth, Rene Worzischek, Felix Streicher...
CMSB
2006
Springer
14 years 3 months ago
Randomization and Feedback Properties of Directed Graphs Inspired by Gene Networks
Having in mind the large-scale analysis of gene regulatory networks, we review a graph decimation algorithm, called "leaf-removal", which can be used to evaluate the feed...
M. Cosentino Lagomarsino, P. Jona, B. Bassetti
ICES
2003
Springer
114views Hardware» more  ICES 2003»
14 years 4 months ago
Evolving Fractal Proteins
The fractal protein is a new concept for improving evolvability, scalability, exploitability and providing a rich medium for evolution. Here the idea of fractal proteins is introdu...
Peter J. Bentley
ECAL
2003
Springer
14 years 4 months ago
Evolving Fractal Gene Regulatory Networks for Robot Control
Fractal proteins are a new evolvable method of mapping genotype to phenotype through a developmental process, where genes are expressed into proteins comprised of subsets of the Ma...
Peter J. Bentley
GLVLSI
2003
IEEE
175views VLSI» more  GLVLSI 2003»
14 years 4 months ago
A custom FPGA for the simulation of gene regulatory networks
We present a unique FPGA that uses a mix of digital and large-signal analog computation for the simulation of gene regulatory networks. The prototype IC consists of a 4x5 array of...
Ilias Tagkopoulos, Charles A. Zukowski, German Cav...
ECCB
2003
IEEE
14 years 4 months ago
Gene networks inference using dynamic Bayesian networks
This article deals with the identification of gene regulatory networks from experimental data using a statistical machine learning approach. A stochastic model of gene interactio...
Bruno-Edouard Perrin, Liva Ralaivola, Aurél...