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NAR
2007
131views more  NAR 2007»
13 years 12 months ago
CRISPRFinder: a web tool to identify clustered regularly interspaced short palindromic repeats
Clustered regularly interspaced short palindromic repeats (CRISPRs) constitute a particular family of tandem repeats found in a wide range of prokaryotic genomes (half of eubacter...
Ibtissem Grissa, Gilles Vergnaud, Christine Pource...
BMCBI
2007
116views more  BMCBI 2007»
14 years 13 days ago
MED: a new non-supervised gene prediction algorithm for bacterial and archaeal genomes
Background: Despite a remarkable success in the computational prediction of genes in Bacteria and Archaea, a lack of comprehensive understanding of prokaryotic gene structures pre...
Huaiqiu Zhu, Gang-Qing Hu, Yi-Fan Yang, Jin Wang, ...
BMCBI
2007
113views more  BMCBI 2007»
14 years 13 days ago
PILER-CR: Fast and accurate identification of CRISPR repeats
Background: Sequencing of prokaryotic genomes has recently revealed the presence of CRISPR elements: short, highly conserved repeats separated by unique sequences of similar lengt...
Robert C. Edgar
BMCBI
2006
108views more  BMCBI 2006»
14 years 15 days ago
Promoter prediction and annotation of microbial genomes based on DNA sequence and structural responses to superhelical stress
Background: In our previous studies, we found that the sites in prokaryotic genomes which are most susceptible to duplex destabilization under the negative superhelical stresses t...
Huiquan Wang, Craig J. Benham
BMCBI
2010
122views more  BMCBI 2010»
14 years 17 days ago
Simultaneous prediction of transcription factor binding sites in a group of prokaryotic genomes
Background: Our current understanding of transcription factor binding sites (TFBSs) in sequenced prokaryotic genomes is very limited due to the lack of an accurate and efficient c...
Shaoqiang Zhang, Shan Li, Phuc T. Pham, Zhengchang...
APBC
2004
14 years 1 months ago
EMAGEN: An Efficient Approach to Multiple Whole Genome Alignment
Following advances in biotechnology, many new whole genome sequences are becoming available every year. A lot of useful information can be derived from the alignment and compariso...
Jitender S. Deogun, Jingyi Yang, Fangrui Ma