NAR
2011
13 years 6 months ago
2011
The polyglutamine diseases are caused in part by a gain-of-function mechanism of neuronal toxicity involving protein conformational changes that result in the formation and deposi...
RECOMB
2007
Springer
14 years 11 months ago
2007
Springer
Abstract. Protein conformational changes play a critical role in biological functions such as ligand-protein and protein-protein interactions. Due to the noise in structural data, ...