NAR
2011
13 years 1 months ago
2011
The stability, localization and translation rate of mRNAs are regulated by a multitude of RNAbinding proteins (RBPs) that find their targets directly or with the help of guide RNA...
NAR
2011
13 years 1 months ago
2011
AREsite is an online resource for the detailed investigation of AU-rich elements (ARE) in vertebrate mRNA 30 -untranslated regions (UTRs). AREs are one of the most prominent cis-a...
BIOCOMP
2009
13 years 8 months ago
2009
- Identification and annotation of all the functional elements in the genome, including genes and regulatory sequences, is a fundamental challenge in genomics and computational bio...
BMCBI
2005
13 years 10 months ago
2005
Background: Cis-regulatory modules are combinations of regulatory elements occurring in close proximity to each other that control the spatial and temporal expression of genes. Th...
BMCBI
2005
13 years 10 months ago
2005
Background: Collections of transcription factor binding profiles (Transfac, Jaspar) are essential to identify regulatory elements in DNA sequences. Subsets of highly similar profi...
BMCBI
2007
13 years 11 months ago
2007
Background: Completion of the human genome sequence along with other species allows for greater understanding of the biochemical mechanisms and processes that govern healthy as we...
BMCBI
2010
13 years 11 months ago
2010
Background: Functional genomic studies involving high-throughput sequencing and tiling array applications, such as ChIP-seq and ChIP-chip, generate large numbers of experimentally...
PSB
2004
14 years 6 days ago
2004
This paper introduces the first integrated algorithm designed to discover novel motifs in heterogeneous sequence data, which is comprised of coregulated genes from a single genome...
IPPS
2003
IEEE
14 years 4 months ago
2003
IEEE
The detection of regulatory elements from a large set of regulatory regions is a challenging problem in computational genomics. However, computational methods to extract this biol...