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    BMCBI
    2007
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    A structural analysis of in vitro catalytic activities of hammerhead ribozymes
    13 years 11 months ago
    A structural analysis of in vitro catalytic activities of hammerhead ribozymes
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    Background: Ribozymes are small catalytic RNAs that possess the dual functions of sequencespecific RNA recognition and site-specific cleavage. Trans-cleaving ribozymes can inhibit...
    Yu Shao, Susan Wu, Chi Yu Chan, Jessie R. Klapper,...
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    BMCBI
    2006
    88views more  BMCBI 2006»
    RiboSubstrates: a web application addressing the cleavage specificities of ribozymes in designated genomes
    13 years 11 months ago
    RiboSubstrates: a web application addressing the cleavage specificities of ribozymes in designated genomes
    Download  www.biomedcentral.com
    Background: RNA-dependent gene silencing is becoming a routine tool used in laboratories worldwide. One of the important remaining hurdles in the selection of the target sequence,...
    Jean-François Lucier, Lucien Junior Bergero...
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