NAR
2010
13 years 6 months ago
2010
High-throughput gene-expression studies result in lists of differentially expressed genes. Most current meta-analyses of these gene lists include searching for significant members...
APCCM
2009
14 years 19 days ago
2009
In life science, deeper understanding of biomolecular systems is acquired by computational modeling and analysis. For the modeling of several kinds of reaction networks, e.g. sign...
BIOCOMP
2006
14 years 28 days ago
2006
Intracellular signaling pathways as well as the interactions and coordination that exist among them are complex and difficult to visualize and understand. Computer-based models of...
SSDBM
2006
IEEE
14 years 5 months ago
2006
IEEE
Signaling pathways are chains of interacting proteins, through which the cell converts a (usually) extracellular signal into a biological response. The number of known signaling p...
CMSB
2009
Springer
14 years 6 months ago
2009
Springer
Systems of ordinary differential equations (ODEs) are often used to model the dynamics of complex biological pathways. We construct a discrete state model as a probabilistic appro...