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NAR
2011
209views Computer Vision» more  NAR 2011»
13 years 2 months ago
CancerResource: a comprehensive database of cancer-relevant proteins and compound interactions supported by experimental knowled
During the development of methods for cancer diagnosis and treatment, a vast amount of information is generated. Novel cancer target proteins have been identified and many compoun...
Jessica Ahmed, Thomas Meinel, Mathias Dunkel, Manu...
BMCBI
2005
61views more  BMCBI 2005»
13 years 11 months ago
Proteins with two SUMO-like domains in chromatin-associated complexes: The RENi (Rad60-Esc2-NIP45) family
Background: Post-translational modification by Small Ubiquitin-like Modifiers (SUMO) has been implicated in protein targeting, in the maintenance of genomic integrity and in trans...
Maria Novatchkova, Andreas Bachmair, Birgit Eisenh...
BMCBI
2008
172views more  BMCBI 2008»
13 years 11 months ago
Classification of drug molecules considering their IC50 values using mixed-integer linear programming based hyper-boxes method
Background: A priori analysis of the activity of drugs on the target protein by computational approaches can be useful in narrowing down drug candidates for further experimental t...
Pelin Armutlu, Muhittin Emre Ozdemir, Fadime Ü...
BMCBI
2010
117views more  BMCBI 2010»
13 years 11 months ago
Identification of NAD interacting residues in proteins
Background: Small molecular cofactors or ligands play a crucial role in the proper functioning of cells. Accurate annotation of their target proteins and binding sites is required...
Hifzur Rahman Ansari, Gajendra P. S. Raghava