— In this paper, two designs for optimal Automated Guided Vehicle (AGV) transportation systems are presented. One is vertical and the other, horizontal. For these systems, the hybrid design methodology proposed here is used. Therefore, we describe how to model and formulate these transportation systems and derive the design parameters, that is, the optimal design solutions. We next evaluate these two transportation systems based on the various transportation requirements, that is, the demands from a port authority. For this purpose, we compare the systems based on the total costs in constructing them. Finally, the evaluation and analytical results are provided, and the most convenient system is presented based on the validity of each system for the given demand.