The contribution presents a multi-agent technology in the domain of the air-traffic control of several autonomous aerial vehicles (manned as well as unmanned). The system has been validated mainly by the collision avoidance (CA) tasks. Several cooperative and non-cooperative CA methods have been integrated in the system to validate and compare their properties in the scalable experiments. The AGENTFLY system is suitable also for the developing and testing of algorithms for the collective flight control. The operation of the underlying multi-agent system has been integrated with freely available geographical and tactical data sources. The system provides real time 2D/3D visualization and also the web-access component. Categories and Subject Descriptors I.2.11 [Computing Methodologies]: Artificial intelligence-Multi-agent systems; I.6 [Computing Methodologies]: Simulation and modeling General Terms Algorithms, Experimentation, Verification Keywords agent-based collision avoidance, auton...