Static Analysis of a Model of the LDL Degradation Pathway

BioAmbients is a derivative of mobile ambients that has shown promise of describing interesting features of the behaviour of biological systems. As for other ambient calculi static program analysis can be used to compute safe approximations of the behaviour of system models. We use these tools to model and analyse the production of cholesterol in living cells and show that we are able to pinpoint the difference in behaviour between models of healthy systems and models of mutated systems giving rise to known diseases.

• Type: Conference
• Year: 2006
• Where: DAGSTUHL
• Authors: Henrik Pilegaard, Hanne Riis Nielson, Flemming Nielson
• Keywords: Calculi Static Program, DAGSTUHL 2006, DAGSTUHL 2007, Mobile Ambients, Systems Giving Rise