The Repetitive Sequence Database and Mining Putative Regulatory Elements in Gene Promoter Regions

At least 43% of the human genome is occupied by repetitive elements. Moreover, around 51% of the rice genome is occupied by repetitive elements. The analysis of repetitive elements reveals that repetitive elements in our genome may have been very important in the evolutionary genomics. The rst part of this study is to describe a database of repetitive elements--RSDB. The RSDB database contains repetitive elements, which are classi ed into the following categories: exact, tandem, and similar. The interfaces needed to query and show the results and statistical data, such as the relationship between repetitive elements and genes, cross-references of repetitive elements among different organisms, and so on, are provided. The second part of this study then attempts to mine the putative binding site for information on how combinations of the known regulatory sites and overrepresented repetitive elements in RSDB are distributed in the promoter regions of groups of functionally related genes....

• Type: Journal
• Year: 2002
• Where: JCB
• Authors: Jorng-Tzong Horng, Hsien-Da Huang, Ming-Hui Jin, Li-Cheng Wu, Shir-Ly Huang
• Keywords: JCB 2002, Overrepresented Repetitive Elements, Putative Binding Sites, Repetitive Elements