In the last decade, instruction-set simulators have become an essential development tool for the design of new programmable architectures. Consequently, the simulator performance is a key factor for the overall design efficiency. Based on the extremely poor performance of commonly used interpretive simulators, research work on fast compiled instruction-set simulation was started ten years ago. However, due to the restrictiveness of the compiled technique, it has not been able to push through in commercial products. This paper presents a new retargetable simulation technique which combines the performance of traditional compiled simulators with the flexibility of interpretive simulation. This technique is not limited to any class of architectures or applications and can be utilized from architecture exploration up to end-user software development. The work-flow and the applicability of the so-called just-intime cache compiled simulation (JIT-CCS) technique will be demonstrated by means...