BRENDA, the enzyme information system in 2011

The BRENDA (BRaunschweig ENzyme Database, http://www.brenda-enzymes.org) enzyme information system is the main collection of enzyme functional and property data for the scientific community. The majority of the data are manually extracted from the primary literature. The content covers information on function, structure, occurrence, preparation and application of enzymes as well as properties of mutants and engineered variants. The number of manually annotated references increased by 30% to more than 100 000, the number of ligand structures by 45% to almost 100 000. New query, analysis and data management tools were implemented to improve data processing, data presentation, data input and data access. BRENDA now provides new viewing options such as the display of the statistics of functional parameters and the 3D view of protein sequence and structure features. Furthermore a ligand summary shows comprehensive information on the BRENDA ligands. The enzymes are linked to their respectiv...

• Type: Journal
• Year: 2011
• Where: NAR
• Authors: Maurice Scheer, Andreas Grote, Antje Chang, Ida Schomburg, Cornelia Munaretto, Michael Rother, Carola Söhngen, Michael Stelzer, Juliane Thiele, Dietmar Schomburg
• Keywords: BRENDA, BRENDA Kinetic Data, Computer Vision, Enzymes, NAR 2011