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NAR
2011
307views Computer Vision» more  NAR 2011»
13 years 2 months ago
BRENDA, the enzyme information system in 2011
The BRENDA (BRaunschweig ENzyme Database, http://www.brenda-enzymes.org) enzyme information system is the main collection of enzyme functional and property data for the scientific...
Maurice Scheer, Andreas Grote, Antje Chang, Ida Sc...
BMCBI
2010
148views more  BMCBI 2010»
13 years 2 months ago
SKPDB: a structural database of shikimate pathway enzymes
Background: The functional and structural characterisation of enzymes that belong to microbial metabolic pathways is very important for structure-based drug design. The main inter...
Helen A. Arcuri, Geraldo F. D. Zafalon, Evandro A....
BMCBI
2010
155views more  BMCBI 2010»
13 years 4 months ago
BrEPS: a flexible and automatic protocol to compute enzyme-specific sequence profiles for functional annotation
Background: Models for the simulation of metabolic networks require the accurate prediction of enzyme function. Based on a genomic sequence, enzymatic functions of gene products a...
Constantin Bannert, A. Welfle, C. aus dem Spring, ...
NAR
2000
107views more  NAR 2000»
13 years 7 months ago
LIGAND: chemical database of enzyme reactions
LIGAND is a composite database comprising three sections: ENZYME for the information of enzyme molecules and enzymatic reactions, COMPOUND for the information of metabolites and o...
Susumu Goto, Takaaki Nishioka, Minoru Kanehisa
NAR
2000
156views more  NAR 2000»
13 years 7 months ago
The ENZYME database in 2000
The ENZYME database is a repository of information related to the nomenclature of enzymes. In recent years it has became an indispensable resource for the development of metabolic...
Amos Bairoch
BMCBI
2007
127views more  BMCBI 2007»
13 years 7 months ago
CORRIE: enzyme sequence annotation with confidence estimates
Using a previously developed automated method for enzyme annotation, we report the reannotation of the ENZYME database and the analysis of local error rates per class. In control ...
Benjamin Audit, Emmanuel D. Levy, Walter R. Gilks,...
BMCBI
2006
149views more  BMCBI 2006»
13 years 7 months ago
REtools: A laboratory program for restriction enzyme work: enzyme selection and reaction condition assistance
Background: Restriction enzymes are one of the everyday tools used in molecular biology. The continuously expanding panel of known restriction enzymes (several thousands) renders ...
Patrick Martin, Kim E. Boulukos, Philippe Pognonec
BMCBI
2008
189views more  BMCBI 2008»
13 years 7 months ago
AnEnPi: identification and annotation of analogous enzymes
Background: Enzymes are responsible for the catalysis of the biochemical reactions in metabolic pathways. Analogous enzymes are able to catalyze the same reactions, but they prese...
Thomas D. Otto, Ana Carolina R. Guimarães, ...
BMCBI
2007
80views more  BMCBI 2007»
13 years 7 months ago
A network perspective on the topological importance of enzymes and their phylogenetic conservation
Background: A metabolic network is the sum of all chemical transformations or reactions in the cell, with the metabolites being interconnected by enzyme-catalyzed reactions. Many ...
Wei-chung Liu, Wen-hsien Lin, Andrew J. Davis, Fer...
IMECS
2007
13 years 9 months ago
Pseudo-Reverse Approach in Genetic Evolution: An Empirical Study with Enzymes
— A pseudo-reverse approach is presented in this paper to analyze the evolutionary behaviour of enzymes. It employs the standard model of Nei and Gojobori [1] in a generalized fo...
Sukanya Manna, Cheng-Yuan Liou