Background: Risk for complex disease is thought to be controlled by multiple genetic risk factors, each with small individual effects. Meta-analyses of several independent studies...
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Link prediction is an important task in social networks and data mining for understanding the mechanisms by which the social networks form and evolve. In most link prediction rese...
Learning the structure of a gene regulatory network from time-series gene expression data is a significant challenge. Most approaches proposed in the literature to date attempt to ...
The identification of genes that influence the risk of common, complex diseases primarily through interactions with other genes and environmental factors remains a statistical and ...
Marylyn D. Ritchie, Christopher S. Coffey, Jason H...