Transcriptional factors (TFs) and many of their target genes are involved in gene regulation at the level of transcription. To decipher gene regulatory networks (GRNs) we require ...
C. Jiang, Zhenyu Xuan, Fang Zhao, Michael Q. Zhang
Background: Gene expression programs depend on recognition of cis elements in promoter region of target genes by transcription factors (TFs), but how TFs regulate gene expression ...
Abstract. This paper introduces a model for simulating regulatory networks that is capable of reproducing spatial and temporal expression patterns in developmental processes. The m...
We present an application for integrated visualization of gene expression data from time series experiments in gene regulation networks and metabolic networks. Such integration is...
Starting from the logical description of gene regulatory networks developed by R. Thomas, we introduce an enhanced modelling approach based on timed automata. We obtain a refined ...