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BMCBI
2007
247views more  BMCBI 2007»
13 years 8 months ago
A survey of DNA motif finding algorithms
Background: Unraveling the mechanisms that regulate gene expression is a major challenge in biology. An important task in this challenge is to identify regulatory elements, especi...
Modan K. Das, Ho-Kwok Dai
EDBT
2009
ACM
241views Database» more  EDBT 2009»
14 years 2 months ago
GADDI: distance index based subgraph matching in biological networks
Currently, a huge amount of biological data can be naturally represented by graphs, e.g., protein interaction networks, gene regulatory networks, etc. The need for indexing large ...
Shijie Zhang, Shirong Li, Jiong Yang
RECOMB
2006
Springer
14 years 8 months ago
Identifiability Issues in Phylogeny-Based Detection of Horizontal Gene Transfer
Prokaryotic organisms share genetic material across species boundaries by means of a process known as horizontal gene transfer (HGT). Detecting this process bears great significanc...
Cuong Than, Derek A. Ruths, Hideki Innan, Luay Nak...
AB
2008
Springer
14 years 2 months ago
Local Structure and Behavior of Boolean Bioregulatory Networks
Abstract. A well-known discrete approach to modeling biological regulatory networks is the logical framework developed by R. Thomas. The network structure is captured in an interac...
Heike Siebert
BMCBI
2007
153views more  BMCBI 2007»
13 years 8 months ago
Estimating genealogies from linked marker data: a Bayesian approach
Background: Answers to several fundamental questions in statistical genetics would ideally require knowledge of the ancestral pedigree and of the gene flow therein. A few examples...
Dario Gasbarra, Matti Pirinen, Mikko J. Sillanp&au...