44 search results - page 4 / 9 » A Discriminative Framework for Detecting Remote Protein Homo... |
CIBCB
2005
IEEE
14 years 2 months ago
2005
IEEE
— Part of the challenge of modeling protein sequences is their discrete nature. Many of the most powerful statistical and learning techniques are applicable to points in a Euclid...
BMCBI
2007
13 years 8 months ago
2007
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
IJDMB
2008
13 years 8 months ago
2008
: Computational classification of proteins using methods such as string kernels and Fisher-SVM has demonstrated great success. However, the resulting models do not offer an immedia...
BMCBI
2006
13 years 8 months ago
2006
Background: Detecting remote homologies by direct comparison of protein sequences remains a challenging task. We had previously developed a similarity score between sequences, cal...
BMCBI
2006
2006
On single and multiple models of protein families for the detection of remote sequence relationships
13 years 8 months ago
Background: The detection of relationships between a protein sequence of unknown function and a sequence whose function has been characterised enables the transfer of functional a...